Deprecated: Creation of dynamic property ECAE_The_Post::$opt is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/the-post.php on line 6

Deprecated: Using ${var} in strings is deprecated, use {$var} instead in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/includes/admin-options.php on line 279

Deprecated: Using ${var} in strings is deprecated, use {$var} instead in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/includes/admin-options.php on line 288

Deprecated: Using ${var} in strings is deprecated, use {$var} instead in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/includes/admin-options.php on line 293

Deprecated: Return type of Aventura\Wprss\Core\DataObject::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/includes/Aventura/Wprss/Core/DataObject.php on line 783

Deprecated: Return type of Aventura\Wprss\Core\DataObject::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/includes/Aventura/Wprss/Core/DataObject.php on line 808

Deprecated: Return type of Aventura\Wprss\Core\DataObject::offsetSet($offset, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/includes/Aventura/Wprss/Core/DataObject.php on line 770

Deprecated: Return type of Aventura\Wprss\Core\DataObject::offsetUnset($offset) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/includes/Aventura/Wprss/Core/DataObject.php on line 795

Deprecated: Using ${var} in strings is deprecated, use {$var} instead in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-feed-to-post/includes/wprss-ftp-display.php on line 101

Warning: Trying to access array offset on value of type null in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-feed-to-post/includes/wprss-ftp-help.php on line 11

Deprecated: explode(): Passing null to parameter #2 ($string) of type string is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-feed-to-post/includes/wprss-ftp-help.php on line 11

Deprecated: Return type of RebelCode\Wpra\Core\Data\AbstractDataSet::offsetExists($key) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/src/Data/AbstractDataSet.php on line 44

Deprecated: Return type of RebelCode\Wpra\Core\Data\AbstractDataSet::offsetGet($key) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/src/Data/AbstractDataSet.php on line 24

Deprecated: Return type of RebelCode\Wpra\Core\Data\AbstractDataSet::offsetSet($key, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/src/Data/AbstractDataSet.php on line 60

Deprecated: Return type of RebelCode\Wpra\Core\Data\AbstractDataSet::offsetUnset($key) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/src/Data/AbstractDataSet.php on line 76

Deprecated: Return type of RebelCode\Wpra\Core\Data\AbstractDataSet::offsetExists($key) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/src/Data/AbstractDataSet.php on line 44

Deprecated: Return type of RebelCode\Wpra\Core\Entities\Collections\WpEntityCollection::offsetGet($key) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/src/Entities/Collections/WpEntityCollection.php on line 97

Deprecated: Return type of RebelCode\Wpra\Core\Data\AbstractDataSet::offsetSet($key, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/src/Data/AbstractDataSet.php on line 60

Deprecated: Return type of RebelCode\Wpra\Core\Data\AbstractDataSet::offsetUnset($key) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/src/Data/AbstractDataSet.php on line 76

Deprecated: Return type of Twig\Node\Node::count() should either be compatible with Countable::count(): int, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/vendor/twig/twig/src/Node/Node.php on line 213

Deprecated: Return type of Twig\Node\Node::getIterator() should either be compatible with IteratorAggregate::getIterator(): Traversable, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/wp-rss-aggregator/vendor/twig/twig/src/Node/Node.php on line 221

Deprecated: Optional parameter $field_choices declared before required parameter $location is implicitly treated as a required parameter in /home/dh_swjabf/stopph.org/wp-content/themes/charity-wpl/inc/library.php on line 1132

Deprecated: Return type of Stripe\Util\AutoPagingIterator::current() should either be compatible with Iterator::current(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Util/AutoPagingIterator.php on line 23

Deprecated: Return type of Stripe\Util\AutoPagingIterator::next() should either be compatible with Iterator::next(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Util/AutoPagingIterator.php on line 36

Deprecated: Return type of Stripe\Util\AutoPagingIterator::key() should either be compatible with Iterator::key(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Util/AutoPagingIterator.php on line 31

Deprecated: Return type of Stripe\Util\AutoPagingIterator::valid() should either be compatible with Iterator::valid(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Util/AutoPagingIterator.php on line 55

Deprecated: Return type of Stripe\Util\AutoPagingIterator::rewind() should either be compatible with Iterator::rewind(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Util/AutoPagingIterator.php on line 18

Deprecated: Return type of Stripe\Util\CaseInsensitiveArray::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Util/CaseInsensitiveArray.php on line 36

Deprecated: Return type of Stripe\Util\CaseInsensitiveArray::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Util/CaseInsensitiveArray.php on line 48

Deprecated: Return type of Stripe\Util\CaseInsensitiveArray::offsetSet($offset, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Util/CaseInsensitiveArray.php on line 26

Deprecated: Return type of Stripe\Util\CaseInsensitiveArray::offsetUnset($offset) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Util/CaseInsensitiveArray.php on line 42

Deprecated: Return type of Stripe\Util\Set::getIterator() should either be compatible with IteratorAggregate::getIterator(): Traversable, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Util/Set.php on line 40

Deprecated: Return type of Stripe\StripeObject::offsetExists($k) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/StripeObject.php on line 186

Deprecated: Return type of Stripe\StripeObject::offsetGet($k) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/StripeObject.php on line 196

Deprecated: Return type of Stripe\StripeObject::offsetSet($k, $v) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/StripeObject.php on line 181

Deprecated: Return type of Stripe\StripeObject::offsetUnset($k) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/StripeObject.php on line 191

Deprecated: Return type of Stripe\StripeObject::count() should either be compatible with Countable::count(): int, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/StripeObject.php on line 202

Deprecated: Return type of Stripe\StripeObject::jsonSerialize() should either be compatible with JsonSerializable::jsonSerialize(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/StripeObject.php on line 402

Deprecated: Using ${var} in strings is deprecated, use {$var} instead in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/ApiResource.php on line 85

Deprecated: Using ${var} in strings is deprecated, use {$var} instead in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/SingletonApiResource.php on line 28

Deprecated: Return type of Stripe\Collection::getIterator() should either be compatible with IteratorAggregate::getIterator(): Traversable, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/dh_swjabf/stopph.org/wp-content/plugins/charity-toolskit/vendors/stripe/lib/Collection.php on line 75
News – Stop Pulmonary Hypertension | StopPH.org

News


Deprecated: Creation of dynamic property advExcLoc::$options is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 5

Deprecated: Creation of dynamic property advExcLoc::$content is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 6

Deprecated: Creation of dynamic property advExcLoc::$width is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 7

Deprecated: Creation of dynamic property advExcLoc::$justify is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 8

A bell flanked by two smaller bells is shown with the word "UPDATE" on it.

Pulmonary arterial hypertension (PAH) patients enrolled in a Phase 2b clinical trial testing AV-101, an inhaled formulation of imatinib, entered the trial with significant disease despite use of triple background therapy, according to data shared by developer Aerovate Therapeutics.

The company said the study population will allow for the clear demonstration of AV-101’s clinical benefits in this ongoing part of the IMPAHCT Phase 2/3 trial (NCT05036135), top-line results from which are expected next month. read more


Deprecated: Creation of dynamic property advExcLoc::$options is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 5

Deprecated: Creation of dynamic property advExcLoc::$content is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 6

Deprecated: Creation of dynamic property advExcLoc::$width is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 7

Deprecated: Creation of dynamic property advExcLoc::$justify is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 8

Banner image for "Worth the PHight," a column by Jen Cueva. The graphic illustration depicts a woman with short brown hair and oxygen sitting on the beach and looking out toward the ocean.

Are you or your partner managing pulmonary hypertension (PH)? Does it make going out on traditional dates difficult? If so, don’t worry; I’ve got you covered.

Date nights are essential to any relationship, but they can be challenging with PH and limited energy. That doesn’t mean we have to give up on romantic evenings with loved ones, however.

As May is Date Your Mate Month, I’m offering a column I’ve been thinking about for a while. My husband, Manny, and I try to do something interesting together every month, depending on how I’m feeling and if my PH and chronic pain are controlled. Last month we went to our first San Diego Padres baseball game. It was exhausting, but worth it! I was grateful our outing was on the weekend so I could rest the following day. read more


Deprecated: Creation of dynamic property advExcLoc::$options is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 5

Deprecated: Creation of dynamic property advExcLoc::$content is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 6

Deprecated: Creation of dynamic property advExcLoc::$width is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 7

Deprecated: Creation of dynamic property advExcLoc::$justify is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 8

A pair of lungs are shown struggling to breathe.

AER-901, a new inhaled formulation of imatinib delivered via a specialized device, was predicted to reach 2-3 times higher levels in the lung tissue over standard inhalers among people with forms of pulmonary hypertension (PH), according to new data from Aerami Therapeutics, its developer.

Having been proven to safely deliver imatinib to the lungs in healthy adults in Phase 1 testing, Aerami is planning a Phase 2 platform trial to test the therapy in patients with multiple types of PH, starting with pulmonary arterial hypertension (PAH) and PH associated with interstitial lung disease (ILD). The lung distribution findings and the design of the planned trial were presented by Aerami at a recent scientific conference. read more


Deprecated: Creation of dynamic property advExcLoc::$options is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 5

Deprecated: Creation of dynamic property advExcLoc::$content is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 6

Deprecated: Creation of dynamic property advExcLoc::$width is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 7

Deprecated: Creation of dynamic property advExcLoc::$justify is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 8

An oversized human hand holds a mouse in a laboratory, alongside a rack with a trio of filled vials.

Findings of a new study into pericytes — cells with multiple functions including immune cell regulation — suggest that targeting a protein known as HIF-2alpha, which is involved in the response to low oxygen conditions, or hypoxia, may be a potential therapeutic approach for pulmonary arterial hypertension (PAH).

The study found that HIF-2alpha regulates the transformation of pericytes into smooth muscle-like cells, contributing to blood vessel changes that characterize PAH. Pericytes, which wrap around blood vessel walls, regulate immune cell entry to the brain and control blood flow, among other functions. read more


Deprecated: Creation of dynamic property advExcLoc::$options is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 5

Deprecated: Creation of dynamic property advExcLoc::$content is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 6

Deprecated: Creation of dynamic property advExcLoc::$width is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 7

Deprecated: Creation of dynamic property advExcLoc::$justify is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 8

The word "News" is shown in all capital letters and highlighted.

Researchers have identified two inflammation-related genes — SELE and CCL20 — whose activity could serve as diagnostic biomarkers for the development of pulmonary hypertension (PH) in people with COVID-19.

Further, the team also identified molecules that target these biomarkers as possible therapeutic approaches for managing the complication.

Overall, the findings offer “new insights into the prediction and treatment of COVID-19 complicated with PH in clinical practice,” the researchers wrote. read more


Deprecated: Creation of dynamic property advExcLoc::$options is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 5

Deprecated: Creation of dynamic property advExcLoc::$content is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 6

Deprecated: Creation of dynamic property advExcLoc::$width is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 7

Deprecated: Creation of dynamic property advExcLoc::$justify is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 8

A column banner depicts colorful flowers against a pink background, with the words "Blooming Hope" in large print

When I was diagnosed with pulmonary hypertension (PH) in 1999, the subject of organ transplant was introduced almost immediately. Doctors explained to my parents that PH was terminal, and that transplant, usually of the heart and lungs, was an option for extending life.

For the next 14 years, transplant loomed as a worrisome but distant inevitability. After a thorough fight with PH, a decline in my health during my senior year of high school finally led my PH specialist to push me toward a transplant evaluation. read more


Deprecated: Creation of dynamic property advExcLoc::$options is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 5

Deprecated: Creation of dynamic property advExcLoc::$content is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 6

Deprecated: Creation of dynamic property advExcLoc::$width is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 7

Deprecated: Creation of dynamic property advExcLoc::$justify is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 8

Banner image for "Worth the PHight," a column by Jen Cueva. The graphic illustration depicts a woman with short brown hair and oxygen sitting on the beach and looking out toward the ocean.

I’m often in awe of my body’s resilience.

Imagine this: The windows are wide open, a gentle breeze dances through the room, and warm Southern California sunshine filters through the blinds, casting patterns on the floor. On such days, amid the freshness of the air wafting inside, I find myself lost in thought.

As I flip through old seasons in my mind and scroll through memories on social media, I’m struck by the magnitude of the traumatic experiences I’ve weathered. At times, I was so out of it that I didn’t recognize my family and friends. Reflecting on those challenging times, I’m grateful my story was unfinished. God only knows how I made it through. Yet, here I am, still standing and breathing. I’m thankful for this resilient body of mine. read more


Deprecated: Creation of dynamic property advExcLoc::$options is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 5

Deprecated: Creation of dynamic property advExcLoc::$content is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 6

Deprecated: Creation of dynamic property advExcLoc::$width is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 7

Deprecated: Creation of dynamic property advExcLoc::$justify is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 8

This illustration shows a hand holding a mouse, with test tubes nearby.

Reduced exercise capacity appeared to be a consequence of cardiac and pulmonary changes, but not skeletal muscle alterations, in rat models of pulmonary hypertension (PH), according to recent research.

While no functional problems with muscles could be observed despite obvious impairments in exercise capacity, significant cardiopulmonary dysfunction was already present.

“This study provides direct evidence showing reduced exercise capacity in PH occurs before skeletal muscle dysfunction and suggesting that intrinsic changes in skeletal muscle are not causative to exercise intolerance in PH,” the study’s researchers wrote in “Reduced exercise capacity occurs before intrinsic skeletal muscle dysfunction in experimental rat models of pulmonary hypertension,” which was published in Pulmonary Circulation. read more


Deprecated: Creation of dynamic property advExcLoc::$options is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 5

Deprecated: Creation of dynamic property advExcLoc::$content is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 6

Deprecated: Creation of dynamic property advExcLoc::$width is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 7

Deprecated: Creation of dynamic property advExcLoc::$justify is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 8

banner image for "Phighting Words," a column by Mike Naple, depicting bookshelves filled with books on one side and the Washington Monument on the other

The springtime is when I miss running the most — when the weather starts to warm a little and folks lace up their shoes, go outside, and get a boost of endorphins.

Save for one scary moment in 2021, I don’t run anymore. Not since I left the hospital in 2016 with a diagnosis of pulmonary hypertension (PH), a chronic, progressive disease that affects the heart and lungs. Sometimes living with PH feels like I’m a fish struggling to breathe out of water, which makes it difficult to compete in a 5K. I even refrain from running to catch the bus I take to and from work because of the shortness of breath and chest tightness that will result. Better to just wait for another one to roll by. read more


Deprecated: Creation of dynamic property advExcLoc::$options is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 5

Deprecated: Creation of dynamic property advExcLoc::$content is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 6

Deprecated: Creation of dynamic property advExcLoc::$width is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 7

Deprecated: Creation of dynamic property advExcLoc::$justify is deprecated in /home/dh_swjabf/stopph.org/wp-content/plugins/easy-custom-auto-excerpt/advExcLoc.php on line 8

A bell flanked by two smaller bells is shown with the word "UPDATE" on it.

The U.S. Food and Drug Administration (FDA) has supported Inhibikase Therapeutics‘ Phase 2/3 trial of its experimental formulation of imatinib, called IkT-001Pro, for pulmonary arterial hypertension (PAH), the company reports.

In a meeting, the FDA asked the company to complete a preclinical study in cells to compare IkT-001Pro to imatinib. Cardiovascular abnormalities have been reported with imatinib, a molecule that’s been explored for PAH. The FDA agreed Inhibikase had shown a connection between imatinib’s use in blood and gastrointestinal cancers and PAH, according to the company. read more


Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in /home/dh_swjabf/stopph.org/wp-content/themes/charity-wpl/inc/library.php on line 587

GIVE CHILDREN A PHIGHTING CHANCE